Overview
Nanofinder®HE is a high end microspectroscopy system designed for combined Raman and AFM measurement. Not only confocal Raman measurements but also AFM-Raman/TERS measurements are available with AFM system combined. Switchable microscope configurations such as upright, inverted, transmission are available with a single AFM at single measurement site. The system is equipped with build-in spectrum calibration source and automatical confocal alignment facilities.Up to 4 excitation lasers are available with fully automatical switching. Computer controlled optical path can be exchanged for UV, VIS or NIR spectral range.
“Large Area Scan option” – Fast mapping of big samples
・Raman mapping with step motor stage of millimeter, centimeter or even larger scanning area.
・Fast scan by synchronized constant speed sample movement and data collection.
・Easy switching between point scan and fast scan.
・Combinable with “Line Scan” option.
※Stepping motor stage is required for this scan option.
Application
example 1: Large test grid
Size: 27.5 mm X 3.85 mm
Number of spectra: 218,827 (2,751x77)
Mapping time: ~25 min (~7.2 ms/point)
example 2: Pharmaceutical tablet
Raman intensity Image of
Aspirin (blue) and Paracetamol (red)
distribution.
Aspirin and Paracetamol spectra,
40xNA0.6, exposure 1 min
Size: 7.75 mm X 7.75 mm
Number of spectra: 24,025 (155x155)
Mapping time: 50 min (~125 ms/point)
Detailed specifications
System configuration
| All-In-One device | opto-mechanical unit, spectrometer, microscope, multilaser system and controller are integrated in a single case |
| Granite frame | exclusive optical system stability |
| Multi-configuration microscope | Up-right, Inverted, Transmission - reconfigurable Bright and Dark-field, Fluorescence observation modes; Microscope objective lens turret, TV-CCD camera |
| Scanner | Piezo stage （X-Y-Z） or (X-Y) Stepping Motors or Atomic Force Microscope (AFM) |
| Excitation Raman laser | up to 3 built-in plus 1 external port |
| Spectrometer | assembled on granite base plate, f=55 cm, 2 exit ports, 3 motorized gratings on exchangeable turret |
| Detector | for VIS Raman cooled CCD or EMCCD, for NIR Raman or PL: InGaAs, for Fluorescence Lifetime: APD with TCSPC |
| Computer, LCD | 2 monitors in AFM configuration |
| Software | advanced Nanofinder software set |
3D confocal Raman spectroscopy
| Mapping range | 100×100×20 μm with piezo-stage ＊Standard for AFM combined. Larger range stages up to 300×300×100 μm are also available. |
| Mapping speed | ＜3 ms/point (full spectrum saving)＊With EM CCD ADC 3 MHz. |
| Spatial resolution(typical) | ||||
|---|---|---|---|---|
| Laser Wavelength (nm) | 473 | 532 | 785 | |
| Objective lens 100×0.95(air) | XY(nm) | 200 | 220 | 500 |
| Z(nm) | 500 | 550 | 850 | |
| Objective lens 150×1.25(water) | XY(nm) | 180 | 200 | - |
| Z(nm) | 400 | 420 | - | |
※For laser line : XY-edge responce 10~90 %, Z-surface responce FWHM
| Raman shift measurement range | ||||
|---|---|---|---|---|
| Laser Wavelength (nm) | 473 | 532 | 785 | |
| Wavenumber range(cm-1) with BR-DD CCD |
<150～>4,000 | <60～>4,000 | <60～>3,000 | |
※Low frequency Raman option (＜10cm-1)available.
Detection channel optical path throughput correction option available.
| Spectral resolution: spectral line FWHM | ||||
|---|---|---|---|---|
| Grating (G/mm) | 1800 | 75(Echelle) | ||
| Resolution(cm-1) | 0.8 | 0.25 | ||
- ※Under the following conditions
- 1. At the CCD center.
- 2. Central wavelength 550 nm.
- 3. CCD pixel size 16×16 μm2
| Spectral accuracy: within 1 pixel of CCD | ||||
|---|---|---|---|---|
| Grating (G/mm) | 1800 | 75(Echelle) | ||
| Accuracy(cm-1) | 0.43 | 0.1 | ||
- ※Under the following conditions
- 1. Central wavelength 550 nm
- 2. CCD pixel size 16×16 μm2
| Standard built-in laser set (CW for Raman) | ||||
|---|---|---|---|---|
| Laser wavelength(nm) | 473 | 532 | 785 | 632.8 |
| Power(mW) | 20 | 50 | 80 | 32 |
| Spatial mode | TEM00 | |||
| M2 | < 1.1 | < 1.2 | < 1.1 | |
| Spectral line width(MHz) | < 10 | < 50 | < 160 | |
| Polarization contrast | >100：1 | |||
Spectrometer
| Optical scheme | Czerny-Turner |
| Focal length | 550 mm |
| Entrance slit | 2 motorized crossed slits,independent control, width 0～2 mm |
| Exit ports | 2 |
| Motorized turret | with 3 gratings |
| Grating choice | 150, 300, 600, 1200, 1800, 2400, 3600 G/mm, Echelle(75 G/mm) |
| Grating (G/mm) | 600 | 1800 | 75(Echelle) | |
| Range on CCD | nm | 75.5 | 21.4 | 4.8 |
| cm-1 | 2509 | 708 | 159 | |
| Dispersion | nm/pixel | 0.047 | 0.0134 | 0.0031 |
| cm-1/pixel | 1.55 | 0.44 | 0.1 | |
- ※ Under the following conditions
- 1. Central wavelength 550 nm
- 2. CCD pixel size 16×16μm2
- 3. CCD width is 1600 pixel
Detectors
| Cooled CCD (EMCCD)detector (main) | |
|---|---|
| Maximum cooling | 100 ℃ (water)、 80 ℃ (air) |
| DU970P EMCCD | High-end model with electron multiplying ability High speed 3MHz ADC.Recommended for high speed and high sensitivity measurement. |
| DU920P CCD DU940P CCD |
High speed 3MHz ADC. Recommended for high speed measurement. |
| DU401A CCD DU420A CCD |
100kHz ADC. Low cost model |
AFM
| Model | SmartSPM™1000+HE002 | CombiScope™1000+HE001 | CombiScope™1000+HE002 |
| For combined operation with microscope | Up-right | Inverted | Up-right Inverted Transmission |
| Change microscope objective between low and high magnification with revolver | YES | No | Up-right:YES Inverted:No |
| Max. microscope objective NA for combined AFM-Raman operation | 100×0.7 | 100×1.4 Oil | 100×0.7(top) 100×1.4 Oil(bottom) |
| SPM head positioning(X×Y,mm) | Manual12.7×12.7 | Motorized1.6×1.6 mm Resolution1μm |
Motorized1.6×1.6 mm Resolution1μm |
| Sample size(X×Y,mm) | 40×50×15 | Standard microscope slide and cover glasses | Standard microscope slide and cover glasses |
| Sample positioning(X×Y,mm) | Motorized5×5、Resolution1μm | Manual、25×25 | Manual、25×25 |
| Scanning range(X×Y×Z,μm) | 100×100×15 | 100×100×20 | 100×100×20 |
| Scanner Resonance frequency (unloaded, Hz) | XY：7000 Z：15000 |
XY：450 Z：1100 |
XY：450 Z：1100 |
| Maximum scanning speed (line/sec.) | 50 | 2 | 2 |
| Registration system noise (nm) | <0.1 | <0.03 | <0.1 |
| Scanner noise (nm,rms) | XY：<0.1（F.B.ON） <0.02（F.B.OFF） Z:<0.04（F.B.ON） |
XY：<0.1（F.B.ON） <0.02（F.B.OFF） Z:<0.1（F.B.ON） |
XY：<0.1（F.B.ON） <0.02（F.B.OFF） Z:<0.1（F.B.ON） |
| Operation in liquid | No | Yes (optional) | No |
Adobe Reader is required to view the downloaded PDF files.
Please download it from the left banner and install it.
| Last Updated | Update Information | Size | Download |
|---|
