TOKYO INSTRUMENTS,INC. - Nanofinder®30

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	Product NO : TII-1

	*3D Raman Microscopy System, Micro-Nano Scale Micro spectroscopy Nanofinder®30*

Living cell


Yeast cell. Microscopic image (a), fluorescence GFP image (b). Raman image at 1602 cm^-1 (c) shows the distribution of highly metabolic- active mitochondria.
Raman peak at 1602 cm^-1 shows degradation in metabolic activity due to suppression of respiration by KCN.
Raman band at 1602 cm^-1 is called the "Raman spectroscopic signature of life"
Data courtesy of Prof. Hiro-o Hamaguchi, The University of Tokyo.

Single molecule detection

Fluorescent image			Fluorescence spectrum 20 sec. accumulation

Excitation laser: 532 nm Power: 200 nW Fluorescence peak: 556 nm			Single molecule image disappeared after the single step decay.
Single molecule sample: 5'-Hexachlorofluorescein modified oligonucleotides.
Data courtesy of Dr. M.Ishikawa, AIST.

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